Silent Cerebral Infarct Multi-Center Clinical Trial

Silent Cerebral Infarct Multi-Center Clinical Trial

Issue:  Silent cerebral infarctsCstrokes that do not cause immediately obvious symptomsCfrequently go unrecognized but are one of the most serious complications of SCD.  They can cause declines in school performance, increased forgetfulness, and a diminished ability to follow even simple instructions.  Are blood transfusions effective and safe in preventing them in high-risk children?

Participants:  Children with SCD, 5 to 14 years of age, who have had a cerebral infarct documented by MRI scan

Comparison:   blood transfusions (the experimental treatment)

versus

no intervention (the control)

More Information:  http://www.clinicaltrials.gov/ct2/show/NCT00072761